Proper study design is one of the most important aspects of successful biomarker discovery and that includes both a thorough understanding of the disease population and which statistical tools to use. New research from Arizona State University examines how the predictive reliability of statistical tests relies not only on the choice of the test (clearly) [...]
Research published in the British Journal of Cancer correlates membranous expression of PODXL in urothelial bladder cancer with unfavorable tumor characteristics. The marker demonstrates potential clinical utility for improved treatment stratification of patients.
A study conducted by Dr. Eric Thorin of the Montreal Heart Institute, suggests blood levels of angiopoietin-like protein 2 (angptl2) may represent an early biomarker for atherosclerosis. Researchers discovered levels of angptl2 are six times higher in mice with coronary heart disease than in healthy mice. Their study also revealed angptl2 levels increase with age [...]